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While companies are promoting e-cigarettes to young Canadians, researchers do not yet know how nicotine delivered by these vaping devices affects teenagers’ brains.

“We don’t really know very much at all with respect to [nicotine’s impact on] human adolescents,” said Laurie Zawertailo, senior scientist with the Nicotine Dependence Service at Toronto’s Centre for Addiction and Mental Health.

The vast majority of studies on the effects of the drug on developing adolescent brains have been on laboratory rodents, she said. [...]