Nicotine Science and Policy

By Harry Shapiro July 10, 2026

Harry’s Blog 132: “Zyn! Went The Strings Of My Heart” (with apologies to Judy Garland)

FDA approval of 20 nicotine pouch products is another step forward for tobacco harm reduction

The FDA in the U.S. has granted marketing authorisation for Zyn nicotine pouch products (five variations on mint plus five other flavours in two different strengths).

In its letter to PMI (who own Zyn manufacturers Swedish Match), the FDA wrote:

Based on our review of your MRTPAs [Modified Risk Tobacco Applications] we determined that the proposed modified risk tobacco products, …as actually used by consumers would significantly reduce harm and the risk of tobacco-related disease to individual tobacco users and benefit the health of the population as a whole, taking into account both users of tobacco products and persons who do not currently use tobacco products. Therefore, we authorize marketing of the tobacco products as modified risk tobacco products with the following modified risk information – “Using ZYN instead of cigarettes puts you at a lower risk of mouth cancer, heart disease, lung cancer, stroke, emphysema and chronic bronchitis”.

July 31, 2026 by gfn.tv

Why Prohibition Is Failing Public Health? | GFN Voices 2026 #1

Prohibition can give the impression of control while making the underlying risks harder to manage. When legal access to safer nicotine products is restricted, demand does not disappear; it can shift towards illicit supply, misinformation or continued cigarette use. That is where public health loses ground: not in the intention to reduce harm, but in the failure to account for real-world behaviour. Effective policy should reduce risk where people actually are, not where theory assumes they should be.





July 31, 2026 by substack.com

The History of Safer

Safer nicotine did not appear out of nowhere. Its history is shaped by smokers looking for alternatives, scientists measuring risk, and policies that often struggled to keep up with both. From snus to vaping and nicotine pouches, the same lesson keeps returning: removing combustion can change the health equation. Understanding that history matters, because the future of tobacco policy should not repeat the mistakes that kept cigarettes at the centre for so long.



July 31, 2026 by 2firsts.com

Italy and Greece Oppose Ireland’s Nicotine Product Bill, Raising EU Regulatory Concerns

Italy and Greece challenge Ireland's proposed strict regulations on nicotine products, citing concerns about EU market coordination. The dispute centers on balancing public health goals with market harmonization. Ireland aims to enhance controls on vapes and nicotine pouches, focusing on marketing, packaging, and sales restrictions. This conflict highlights the evolving fragmentation of European nicotine regulations, affecting companies operating across the region. The objections emphasize the need for harmonizing national rules with EU frameworks. The debate underscores the challenges of aligning public health objectives with single market principles in the nicotine industry.


July 31, 2026 by planetofthevapes.co.uk

Ireland is Blocking Switching

Ireland says it wants fewer people smoking, yet its vape policy risks making switching harder. If f…


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July 31, 2026 by planetofthevapes.co.uk

IBVTA Expresses Surprise

Surprise from the vaping sector points to a wider problem: policy is moving faster than the evidence conversation. When responsible retailers and manufacturers are treated as obstacles rather than part of the regulated solution, the legal market becomes weaker and the illicit market gains room. A serious approach should separate youth access, enforcement failures and adult switching instead of folding them into one blunt narrative. Regulation works best when it brings credible actors into accountability, not when it pushes them to the margins.


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11.80% of the adult population are current smokers. There are approximately 6.7 million current smokers in United Kingdom 13.60% of men are current smokers but only 10.10% of women.
SOURCE: GSTHR

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July 31, 2026 by healthday.com

Vaping Is Likely Reshaping The Future Of Cancer In The US, Study Argues

Cancer risk should not be discussed through headlines alone. New modelling on vaping and future cancer burden raises important questions about long-term outcomes, but it also depends on the comparison being made: continued smoking, complete cessation, dual use or full switching. The crucial distinction remains combustion, which drives the overwhelming burden of tobacco-related cancer. Public health communication should examine emerging risks without obscuring the far greater danger of cigarettes.


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14.10% of the adult population are current smokers. There are approximately 39.8 million current smokers in United States 17.10% of men are current smokers but only 11.10% of women.
SOURCE: GSTHR


Blogs

Harry’s Blog 132: “Zyn! Went The Strings Of My Heart” (with apologies to Judy Garland)

FDA approval of 20 nicotine pouch products is another step forward for tobacco harm reduction

The FDA in the U.S. has granted marketing authorisation for Zyn nicotine pouch products (five variations on mint plus five other flavours in two different strengths).

In its letter to PMI (who own Zyn manufacturers Swedish Match), the FDA wrote:

Based on our review of your MRTPAs [Modified Risk Tobacco Applications] we determined that the proposed modified risk tobacco products, …as actually used by consumers would significantly reduce harm and the risk of tobacco-related disease to individual tobacco users and benefit the health of the population as a whole, taking into account both users of tobacco products and persons who do not currently use tobacco products. Therefore, we authorize marketing of the tobacco products as modified risk tobacco products with the following modified risk information – “Using ZYN instead of cigarettes puts you at a lower risk of mouth cancer, heart disease, lung cancer, stroke, emphysema and chronic bronchitis”.

Harry’s Blog 131: Hidden harms

New publications from K•A•C discuss the challenge of smoking in treatment services caring for those who are HIV positive or coping with drug problems.

Smoking rates among those who are HIV positive and those who use drugs (as well as those with mental health problems where there may well be overlap) are anything from two to four times higher than the general adult smoking rates of most developed countries. One study of those receiving opiate substitute treatment recorded a smoking prevalence rate of 85%. Why should this be?

Harry’s blog 130: Follow the science not the money

For the sake of public health, end virtue signalling about THR funding

I arrived into the world of tobacco harm reduction (THR) from drugs and HIV harm reduction in 2015. I was invited into KAC by two valued colleagues from my previous world who were perfectly up front (and have never hidden the fact) that the funding for the organisation came from the Foundation for a Smoke Free World which in turn was funded by Philip Morris International. And the reason that they were prepared to use this money to further the cause of THR was that no other prospective funders for a harm reduction project were interested. Nobody back in the day was excited by the fact that if you could separate nicotine use from combustion the relative risk was massively reduced and the potential health gains enormous.